Open Access Research

Cadmium chloride (CdCl2): a mild and efficient catalyst for the synthesis of benzimidazoles

B Sammaiah, D Sumalatha, GS S Reddy, M Rajeswari and LN Sharada*

Author Affiliations

Department of Chemistry, Osmania University, Koti, Hyderabad, 500195, India

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International Journal of Industrial Chemistry 2012, 3:11 doi:10.1186/2228-5547-3-11

Published: 12 July 2012

Abstract

One-pot synthesis of benzimidazoles has been carried out using ortho-phenylenediamine and aldehydes. The condensation reaction smoothly took place in the presence of a mild Lewis acid cadmium chloride. All the reactions were carried out in acetonitrile at 80°C to 85°C.

Keywords:
Benzimidazoles; Aldehydes; Ortho-phenylenediamine; Cadmium chloride